2-(1-(4-[4-(benzyloxy)phenyl]butyl}-1H-imidazol-2-yl)-1-ethanol → 4-[4-[2-(2-hydroxyethyl)-1H-imidazol-1-yl]butyl]phenol
Reaktionsgleichung
C([O:8][C:9]1[CH:14]=[CH:13][C:12]([CH2:15][CH2:16][CH2:17][CH2:18][N:19]2[CH:23]=[CH:22][N:21]=[C:20]2[CH2:24][CH2:25][OH:26])=[CH:11][CH:10]=1)C1C=CC=CC=1>[C].[Pd]>[OH:26][CH2:25][CH2:24][C:20]1[N:19]([CH2:18][CH2:17][CH2:16][CH2:15][C:12]2[CH:11]=[CH:10][C:9]([OH:8])=[CH:14][CH:13]=2)[CH:23]=[CH:22][N:21]=1Komponenten
3
Edukt 1
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
Using 2-(1-{4-[4-(benzyloxy)phenyl]butyl}-1H-imidazol-2-yl)-1-ethanol (10.67 g) and 10% palladium carbon (1.6 g), the same reaction as Reference Example 11-(v) was carried out to yield the titled compound (5.3 g).
Aufarbeitung
- customthe same reaction as Reference Example 11-(v)