5-methyl-6,7-dihydro-1-benzothiophen-4(5H)-one → 5-Methyl-4,5,6,7-tetrahydro-1-benzothiophen-4-amine

HRID 1612196

Reaktionsgleichung

Reaktionsgleichung von HRID 1612196
O1C2CCCC([NH2:10])C=2C=C1.[CH3:11][CH:12]1[C:20](=O)[C:16]2[CH:17]=[CH:18][S:19][C:15]=2[CH2:14][CH2:13]1>>[CH3:11][CH:12]1[CH:20]([NH2:10])[C:16]2[CH:17]=[CH:18][S:19][C:15]=2[CH2:14][CH2:13]1

Komponenten

3

Edukt 2

HCID 154115085-methyl-6,7-dihydro-1-benzothiophen-4(5H)-oneHCID 185251714,5,6,7-Tetrahydro-1-benzofuran-4-amine

Produkt 1

HCID 203489295-Methyl-4,5,6,7-tetrahydro-1-benzothiophen-4-amine

Versuchsvorschrift

Following the procedure for the preparation of 4,5,6,7-tetrahydro-1-benzofuran-4-amine but substituting 5-methyl-6,7-dihydro-1-benzothiophen-4(5H)-one and making non-critical variations provided the title compound as a oil: 1H NMR (400 MHz, CDCl3) δ) 7.12-6.99, 4.13, 3.89, 3.51, 2.86-2.74, 2.13-1.98, 1.75, 1.65, 1.15, 1.07.

Quellen und Nachweise

ORD-Eintrag
ord-745e4ebddcb044ac969cd954e732949c
Quelldatensatz
uspto-grants-2006_01
Patentnummer
US06992087B2

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