HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1613150Erstellt: 26. Oktober 2026
Sodium Carbonate → 3-Bromo-5-cyano-4'-t-butyldiphenylsilyloxvmethylbiphenyl
https://huagongshe.com/reaction/1613150
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Sodium Carbonate | HCID 10340 | — |
| Edukt | 3,5-Dibromobenzonitrile | HCID 2797690 | — |
| Edukt | (4-(((tert-Butyldiphenylsilyl)oxy)methyl)phenyl)boronic acid | HCID 15224568 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Lösungsmittel | Toluene | HCID 1140 | — |
| Produkt | 3-Bromo-5-cyano-4'-t-butyldiphenylsilyloxvmethylbiphenyl | HCID 19432436 | — |
Reaktionsschritte
A mixture of 1.49 g (3.83 mmoles) of boronic acid derivative from Example 4, 2.0 g (7.67 mmoles) of 3,5-dibromobenzonitrile, and 133 mg (0.1 mmoles) of tetrakistriphenylphosphine in 16 mL toluene and 3.4 mL 95% ethanol with 3.47 mL (6.97 mmoles) of 2 N sodium carbonate was stirred vigorously at 80° C. under nitrogen for 3.5 hours.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patentnummer | US05192758 |
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| Quelldatensatz | uspto-grants-1993_03 |
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| ORD ID | ord-c5c790c91d80442d82ab6c48d9a49b40 |
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| Quellennotiz | uspto-grants-1993_03 |
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