Carbonic acid-guanidine (1:1) → HCID 178493423, Verbindung

HRID 1617199Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1617199
[OH:1][C:2]1[CH:17]=[CH:16][C:5]([CH2:6][CH:7]([C:13](=O)[CH3:14])[C:8](OCC)=[O:9])=[C:4]([O:18][CH3:19])[CH:3]=1.C(=O)(O)O.[NH2:24][C:25]([NH2:27])=[NH:26]>CCO>[NH2:27][C:25]1[N:26]=[C:8]([OH:9])[C:7]([CH2:6][C:5]2[CH:16]=[CH:17][C:2]([OH:1])=[CH:3][C:4]=2[O:18][CH3:19])=[C:13]([CH3:14])[N:24]=1

Komponenten

4

Edukt 2

HCID 286947Carbonic acid-guanidine (1:1)HCID 68415133Ethyl 2-(4-hydroxy-2-methoxybenzyl)-3-oxobutanoate

Produkt 1

HCID 178493423HCID 178493423, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

A mixture of the product from step (ii) (23.35 g) and guanidine carbonate (15.9 g) in EtOH (300 ml) was heated under reflux for 24 h. The mixture was cooled and the solid filtered and washed with EtOH, water, EtOH then diethyl ether and dried to afford the subtitle compound, 11.36 g.

Aufarbeitung

  1. temperaturewas heated
  2. temperatureunder reflux for 24 h
  3. temperatureThe mixture was cooled
  4. filtrationthe solid filtered
  5. washwashed with EtOH, water, EtOH
  6. dry with materialdiethyl ether and dried

Quellen und Nachweise

ORD-Eintrag
ord-95c0ad2605c648febc425fd5a56f843c
Quelldatensatz
uspto-grants-2014_07
Patentnummer
US08765939B2

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