4-Bromo-2-methylpyridine → 1-(2-Methyl-pyridin-4-yl)-3,3-diphenyl-propan-1-one
Reaktionsgleichung
CON(C)[C:4](=[O:19])[CH2:5][CH:6]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1.Br[C:22]1[CH:27]=[CH:26][N:25]=[C:24]([CH3:28])[CH:23]=1>>[CH3:28][C:24]1[CH:23]=[C:22]([C:4](=[O:19])[CH2:5][CH:6]([C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=2)[C:13]2[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=2)[CH:27]=[CH:26][N:25]=1Komponenten
3
Versuchsvorschrift
In analogy to example 55, step 2, the title compounds was prepared from N-methoxy-N-methyl-3,3-diphenyl-propionamide and 4-bromo-2-methylpyridine as a colorless oil, MS (ESI+): m/z=302.15 ([M+H]+).
Quellen und Nachweise
- ORD-Eintrag
- ord-ef5083a14cbb4643896fdc0188aec3a7
- Quelldatensatz
- uspto-grants-2014_07
- Patentnummer
- US08765730B2