4-Methoxycarbonylphenylboronic acid → 3'-[3-(2-Methyl-pyridin-4-yl)-3-oxo-1-o-tolyl-propyl]-biphenyl-4-carboxylic acid methyl ester
Reaktionsgleichung
Br[C:2]1[CH:3]=[C:4]([CH:8]([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=2[CH3:25])[CH2:9][C:10]([C:12]2[CH:17]=[CH:16][N:15]=[C:14]([CH3:18])[CH:13]=2)=[O:11])[CH:5]=[CH:6][CH:7]=1.[CH3:26][O:27][C:28]([C:30]1[CH:35]=[CH:34][C:33](B(O)O)=[CH:32][CH:31]=1)=[O:29]>>[CH3:26][O:27][C:28]([C:30]1[CH:35]=[CH:34][C:33]([C:6]2[CH:7]=[CH:2][CH:3]=[C:4]([CH:8]([C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=3[CH3:25])[CH2:9][C:10]([C:12]3[CH:17]=[CH:16][N:15]=[C:14]([CH3:18])[CH:13]=3)=[O:11])[CH:5]=2)=[CH:32][CH:31]=1)=[O:29]Komponenten
3
Versuchsvorschrift
In analogy to example 19, from 3-(3-bromo-phenyl)-1-(2-methyl-pyridin-4-yl)-3-o-tolyl-propan-1-one (example 98, step 5) and 4-methoxycarbonyl-phenylboronic acid was prepared the title compound as a yellow foam, MS (ESI+): m/z=450.3 ([M+H]+).
Quellen und Nachweise
- ORD-Eintrag
- ord-9dfe1678a2aa4be69e239c6e2cc38fd1
- Quelldatensatz
- uspto-grants-2014_07