HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Oxalyl chloride → N-[(1-Butyl-4-piperidinyl)methyl]5-chloro-2-methylbenzoxazole-7-carboxamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Oxalyl chloride | HCID 65578 | — |
| Edukt | 4-Aminomethyl-1-N-butylpiperidine | HCID 10442133 | — |
| Edukt | 5-Chloro-2-methylbenzoxazole-7-carboxylic acid | HCID 19691864 | — |
| Lösungsmittel | Triethylamine | HCID 8471 | — |
| Produkt | N-[(1-Butyl-4-piperidinyl)methyl]5-chloro-2-methylbenzoxazole-7-carboxamide | HCID 19691850 | — |
Reaktionsschritte
5-Chloro-2-methylbenzoxazole-7-carboxylic acid (Ger. Offen. 2,225,544) is converted to its acid chloride by treatment with oxalyl chloride. The acid chloride is treated with N-(1-butyl-4-piperidinyl)methylamine in the presence of triethylamine to afford the title compound.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05726187 |
| Quelldatensatz | uspto-grants-1998_03 |
| ORD ID | ord-6d542e3dbdd248a898a4ea74dbd0c2eb |
| Quellennotiz | uspto-grants-1998_03 |