4-Sulfanylidene-1,3-thiazolidin-2-one → HCID 178518110, Verbindung
Reaktionsgleichung
[NH2:1][CH2:2][C:3]1([CH2:7][OH:8])[CH2:6][CH2:5][CH2:4]1.S=[C:10]1[CH2:14][S:13][C:12](=[O:15])[NH:11]1>C(O)C>[OH:8][CH2:7][C:3]1([CH2:2][NH:1][C:10]2[CH2:14][S:13][C:12](=[O:15])[N:11]=2)[CH2:6][CH2:5][CH2:4]1Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
To a solution of [1-(aminomethyl)cyclobutyl]methanol (1.00 g) in ethanol (30 mL) was added 4-thioxo-1,3-thiazolidin-2-one (1.16 g), and the mixture was heated under reflux overnight. The reaction mixture was concentrated under reduced pressure, and the obtained powder was washed with ethyl acetate to give the title compound (795 mg).
Aufarbeitung
- temperaturethe mixture was heated
- temperatureunder reflux overnight
- concentrationThe reaction mixture was concentrated under reduced pressure
- washthe obtained powder was washed with ethyl acetate
Quellen und Nachweise
- ORD-Eintrag
- ord-09509325a6e44c5f96c0792b469854ab
- Quelldatensatz
- uspto-grants-2014_07
- Patentnummer
- US08772277B2
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