2-Bromo-5-ethylpyrazine → HCID 71208702, Verbindung
Reaktionsgleichung
[CH3:1][S:2]([C:5]1[CH:10]=[CH:9][C:8]([C:11]2[CH:12]=[C:13]3[CH2:19][CH:18]([CH:20]4[CH2:25][CH2:24][NH:23][CH2:22][CH2:21]4)[O:17][C:14]3=[CH:15][N:16]=2)=[CH:7][CH:6]=1)(=[O:4])=[O:3].Br[C:27]1[CH:32]=[N:31][C:30]([CH2:33][CH3:34])=[CH:29][N:28]=1>CN(C)C=O>[CH2:33]([C:30]1[N:31]=[CH:32][C:27]([N:23]2[CH2:24][CH2:25][CH:20]([CH:18]3[O:17][C:14]4=[CH:15][N:16]=[C:11]([C:8]5[CH:9]=[CH:10][C:5]([S:2]([CH3:1])(=[O:3])=[O:4])=[CH:6][CH:7]=5)[CH:12]=[C:13]4[CH2:19]3)[CH2:21][CH2:22]2)=[N:28][CH:29]=1)[CH3:34]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
The title compound is prepared from 5-(4-methanesulfonyl-phenyl)-2-piperidin-4-yl-2,3-dihydro-furo[2,3-c]pyridine and 2-bromo-5-ethylpyrazine in N,N-dimethylformamide following a procedure analogous to that described in Example 10. LC (method 5): tR=1.25 min; Mass spectrum (ESI+): m/z=465 [M+H]+.