Phosphorus oxychloride → HCID 53407931, Verbindung

HRID 1622332

Reaktionsgleichung

Reaktionsgleichung von HRID 1622332
[CH3:1][C:2]1[C:3](=O)[NH:4][CH:5]=[N:6][CH:7]=1.P(Cl)(Cl)([Cl:11])=O>>[ClH:11].[Cl:11][C:3]1[C:2]([CH3:1])=[CH:7][N:6]=[CH:5][N:4]=1

Komponenten

3

Edukt 2

HCID 24813Phosphorus oxychlorideHCID 2053244-Pyrimidinol, 5-methyl-

Produkt 1

HCID 53407931HCID 53407931, Verbindung

Reaktionsbedingungen

Temperatur
90 °C

Versuchsvorschrift

A mixture of 5-methyl-3H-pyrimidin-4-one (0.60 g, 3.6 mmol) and phosphorous oxychloride (2.0 mL) was heated at 90° C. for 2.5 h. The mixture was evaporated to dryness under reduced pressure and the resultant solid was purified by sublimation under reduced pressure to furnish the title compound as a white solid. This compound was unstable to air and was used immediately in the next step.

Aufarbeitung

  1. customThe mixture was evaporated to dryness under reduced pressure
  2. customthe resultant solid was purified by sublimation under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-5c6992e2e2cc4d99b61018019e5c64be
Quelldatensatz
uspto-grants-2014_07
Patentnummer
US08778925B2

Verknüpfte Notizen

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