Sodium Hydroxide → 4-Butoxy-3-methyl-2-pyridinemethanol

HRID 1623583Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1623583
C([O:4][CH2:5][C:6]1[C:11]([CH3:12])=[C:10]([O:13][CH2:14][CH2:15][CH2:16][CH3:17])[CH:9]=[CH:8][N:7]=1)(=O)C.[OH-].[Na+]>C1(C)C=CC=CC=1>[OH:4][CH2:5][C:6]1[C:11]([CH3:12])=[C:10]([O:13][CH2:14][CH2:15][CH2:16][CH3:17])[CH:9]=[CH:8][N:7]=1

Komponenten

4

Edukt 2

HCID 14798Sodium HydroxideHCID 68469816HCID 68469816, Verbindung

Produkt 1

HCID 684683474-Butoxy-3-methyl-2-pyridinemethanolAusbeute 75,3 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1140TolueneLösungsmittel

Versuchsvorschrift

13.4 g of 2-acetoxymethyl-3-methyl-4-butoxy-pyridine was added dropwise to a 25% aqueous solution of sodium hydroxide, and the mixture was allowed to react for one hour at room temperature. The mixture was diluted with toluene, and then the toluene phase was washed with water, dried over anhydrous magnesium sulfate, and then concentrated to dryness, to obtain 8.3 g of 2-hydroxymethyl-3-methyl-4-butoxy-pyridine as an oily matter.

Aufarbeitung

  1. customto react for one hour at room temperature
  2. washthe toluene phase was washed with water
  3. dry with materialdried over anhydrous magnesium sulfate
  4. concentrationconcentrated to dryness

Quellen und Nachweise

ORD-Eintrag
ord-34f3a2f9b7204100ae38ffa22b5dcef7
Quelldatensatz
uspto-grants-2014_07
Patentnummer
US08778975B2

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