HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol → 4-{6-[(3,4,5-Trimethoxyphenyl)amino]pyrazin-2-yl}phenol
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol | HCID 2734624 | — |
| Edukt | 2-(3,4,5-Trimethoxyphenylamino)-6-chloropyrazine | HCID 11609049 | — |
| Produkt | 4-{6-[(3,4,5-Trimethoxyphenyl)amino]pyrazin-2-yl}phenol | HCID 135453073 | 59,7% |
Reaktionsschritte
Using Method B with 275 mg (0.93 mmol) 2a and 242 mg (1.10 mmol) 4-(4,4,5,5-tetramethyl-1,3,2-dioxoborolan-2-yl)phenol, 83 mg pure title compound (59.7%) were obtained after purification by preparative HPLC (eluent:AcOEt). Reaction time: 48 hours.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07737152B2 |
| Quelldatensatz | uspto-grants-2010_06 |
| ORD ID | ord-4a87b0a24faa4978b9e913d43971f731 |
| Quellennotiz | uspto-grants-2010_06 |