4-Bromo-2-fluorobenzeneboronic acid → [(4'-Bromo-2'-fluorobiphenyl-4-yl)methoxy](tert-butyl)dimethylsilane
Reaktionsgleichung
[C:1]([Si:5]([O:8][CH2:9][C:10]1[CH:15]=[CH:14][C:13](I)=[CH:12][CH:11]=1)([CH3:7])[CH3:6])([CH3:4])([CH3:3])[CH3:2].[Br:17][C:18]1[CH:23]=[CH:22][C:21](B(O)O)=[C:20]([F:27])[CH:19]=1>>[Br:17][C:18]1[CH:23]=[CH:22][C:21]([C:13]2[CH:14]=[CH:15][C:10]([CH2:9][O:8][Si:5]([C:1]([CH3:4])([CH3:3])[CH3:2])([CH3:7])[CH3:6])=[CH:11][CH:12]=2)=[C:20]([F:27])[CH:19]=1Komponenten
3
Versuchsvorschrift
In accordance with Example 4-(2), but using tert-butyl[(4-iodobenzyl)oxy]dimethylsilane instead of tert-butyl[2-(4-iodophenyl)ethoxy]dimethylsilane, and (4-bromo-2-fluorophenyl)boronic acid instead of (4-bromophenyl)boronic acid, the title compound (yield 57%) was afforded as a yellow oil.
Quellen und Nachweise
- ORD-Eintrag
- ord-100d61238a3146448ebfc6e3f5b5ffce
- Quelldatensatz