Dichloromethane → 8-Chloro-7-methyl-4-[3-(6-methyl-pyrazin-2-yl)-phenyl]-1,3-dihydro-benzo[b][1,4]diazepin-2-one

Reaktionsgleichung

[C:1]([O:2][C:3](=[O:4])[NH:7][c:8]1[c:9]([NH:16][C:17]([CH2:18][C:19](=[O:5])[c:21]2[cH:22][c:23](-[c:27]3[n:28][c:29]([CH3:33])[cH:30][n:31][cH:32]3)[cH:24][cH:25][cH:26]2)=[O:34])[cH:10][c:11]([Cl:15])[c:12]([CH3:14])[cH:13]1)([CH3:6])([CH3:20])[CH3:35].[Cl:43][CH2:44][Cl:45].[F:36][C:37]([F:38])([F:39])[C:40]([OH:41])=[O:42]>>[N:7]1=[C:19]([c:21]2[cH:22][c:23](-[c:27]3[n:28][c:29]([CH3:33])[cH:30][n:31][cH:32]3)[cH:24][cH:25][cH:26]2)[CH2:18][C:17](=[O:34])[NH:16][c:9]2[c:8]1[cH:13][c:12]([CH3:14])[c:11]([Cl:15])[cH:10]2