Hydrochloric Acid → Methyl 3-methylazetidine-3-carboxylate hydrochloride

HRID 1629710Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1629710
[CH3:1][O:2][C:3]([C:5]1([CH3:16])[CH2:8][N:7](C(OC(C)(C)C)=O)[CH2:6]1)=[O:4].[ClH:17]>C(Cl)Cl>[ClH:17].[CH3:1][O:2][C:3]([C:5]1([CH3:16])[CH2:8][NH:7][CH2:6]1)=[O:4]

Komponenten

4

Edukt 2

HCID 313Hydrochloric AcidHCID 574158901-Tert-butyl 3-methyl 3-methylazetidine-1,3-dicarboxylate

Produkt 1

HCID 67329141Methyl 3-methylazetidine-3-carboxylate hydrochloride

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

To a solution of INT 13 (1.66 g, 7.24 mmol) in CH2Cl2 was added HCl (2.0 M in Et2O, 36.2 mL, 72.4 mmol). The reaction mixture was stirred at room temperature for 20 hours. The mixture was concentrated to afford INT 14.

Aufarbeitung

  1. concentrationThe mixture was concentrated
  2. customto afford INT 14

Quellen und Nachweise

ORD-Eintrag
ord-76244b54abf84904a71c0776b0fe435c
Quelldatensatz
uspto-grants-2014_07
Patentnummer
US08791100B2

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