L-Serine, N-[(1,1-dimethylethoxy)carbonyl]-O-(phenylmethyl)- → (S)-2-amino-3-(benzyloxy)-N-(4-(4-fluorophenoxy)phenyl)propanamide

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	L-Serine, N-[(1,1-dimethylethoxy)carbonyl]-O-(phenylmethyl)-	HCID 90234	—
Edukt	Benzenamine, 4-(4-fluorophenoxy)-	HCID 147633	—
Produkt	(S)-2-amino-3-(benzyloxy)-N-(4-(4-fluorophenoxy)phenyl)propanamide	HCID 67009137	69%

Reaktionsschritte

Proceeding as in Reference 5, but substituting 4-(4-fluorophenoxy)aniline and (S)-3-(benzyloxy)-2-(tert-butoxycarbonylamino)propanoic acid, gave (S)-2-amino-3-(benzyloxy)-N-(4-(4-fluorophenoxy)phenyl)propanamide (443 mg, 69%).

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08791102B2
Quelldatensatz	uspto-grants-2014_07
ORD ID	ord-1190d9bfb66d475d9c6e486bdaa3f6b2
Quellennotiz	uspto-grants-2014_07