Spiro[4.5]decane-7,9-dione → 9-Isobutyloxyspiro[4.5]dec-8-en-7-one

HRID 1631852

Reaktionsgleichung

Reaktionsgleichung von HRID 1631852
[CH2:1]1[C:5]2([CH2:10][C:9](=[O:11])[CH2:8][C:7](=[O:12])[CH2:6]2)[CH2:4][CH2:3][CH2:2]1>C(O)C(C)C>[CH2:4]([O:12][C:7]1[CH2:6][C:5]2([CH2:1][CH2:2][CH2:3][CH2:4]2)[CH2:10][C:9](=[O:11])[CH:8]=1)[CH:5]([CH3:6])[CH3:1]

Komponenten

3

Edukt 1

HCID 4831594Spiro[4.5]decane-7,9-dione

Produkt 1

HCID 596022189-Isobutyloxyspiro[4.5]dec-8-en-7-oneAusbeute 56 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6560IsobutanolLösungsmittel

Versuchsvorschrift

By following a procedure analogous to that described in Organic Syntheses, Collective Volume 5, p 539, using 81.2 g of spiro[4.5]decane-7,9-dione instead of dihydroresorcinol and isobutyl alcohol instead of ethyl alcohol, a corresponding isobutyl enol ether was prepared. It was purified by silica gel chromatography, obtaining 9-isobutyloxyspiro[4.5]dec-8-en-7-one in a yield of 56%.

Aufarbeitung

  1. customIt was purified by silica gel chromatography

Quellen und Nachweise

ORD-Eintrag
ord-bf9528d150b340abb6cae337d90f33e7
Quelldatensatz
uspto-grants-2014_07
Patentnummer
US08791288B2

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