HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Triethylamine → 4-[(2-Sulfamoyl-5-thienyl)sulfonyl]phenyl 3-(Methoxycarbonyl)propionate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Triethylamine | HCID 8471 | — |
| Edukt | Butanoic acid, 4-chloro-4-oxo-, methyl ester | HCID 73888 | — |
| Edukt | 5-(4-Hydroxyphenyl)sulfonylthiophene-2-sulfonamide | HCID 12736892 | — |
| Lösungsmittel | Acetone | HCID 180 | — |
| Produkt | 4-[(2-Sulfamoyl-5-thienyl)sulfonyl]phenyl 3-(Methoxycarbonyl)propionate | HCID 20442368 | — |
Reaktionsschritte
A solution of 5-[(4-hydroxyphenyl)sulfonyl]thiophene-2-sulfonamide (3.19 g; 0.1 mole) in acetone (60 ml) at -10° was treated with triethylamine (1.11 g; 0.011 mole). Then methoxycarbonylpropionyl chloride (1.66 g; 0.011 mole) was added, dropwise, during 5 minutes at -10°.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04477466 |
| Quelldatensatz | uspto-grants-1984_10 |
| ORD ID | ord-ace74607f05a4b5db29b180e6955764d |
| Quellennotiz | uspto-grants-1984_10 |