Potassium Carbonate → 4-(Phenylsulfamoyl)phenyl 4-ethenylbenzoate

HRID 1633163Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1633163
Br[CH2:2][CH2:3][C:4]1[CH:28]=[CH:27][C:7]([C:8]([O:10][C:11]2[CH:16]=[CH:15][C:14]([S:17](=[O:26])(=[O:25])[NH:18][C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)=[CH:13][CH:12]=2)=[O:9])=[CH:6][CH:5]=1.C(=O)([O-])[O-].[K+].[K+]>CC(C)=O>[CH:3]([C:4]1[CH:28]=[CH:27][C:7]([C:8]([O:10][C:11]2[CH:16]=[CH:15][C:14]([S:17](=[O:25])(=[O:26])[NH:18][C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)=[CH:13][CH:12]=2)=[O:9])=[CH:6][CH:5]=1)=[CH2:2]

Komponenten

4

Edukt 2

HCID 11430Potassium CarbonateHCID 204418094-(Phenylsulfamoyl)phenyl 4-(2-bromoethyl)benzoate

Produkt 1

HCID 204418184-(Phenylsulfamoyl)phenyl 4-ethenylbenzoateAusbeute 76,7 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 180AcetoneLösungsmittel

Versuchsvorschrift

A mixture of 18.5 g (0.0402 mol) of 4-(N-phenylsulfamoyl)phenyl 4-(2-bromoethyl)benzoate, 5.55 g (0.0402 mol) of potassium carbonate and 250 ml of acetone was stirred at room temperature for approximately 48 hours. The mixture was filtered and concentrated to an oily solid. Recrystallization from ethanol:water gave 11.7 g (76.7% of theory) of 4-(N-phenylsulfamoyl)phenyl 4-vinylbenzoate; mp=59°-60° C.

Aufarbeitung

  1. filtrationThe mixture was filtered
  2. concentrationconcentrated to an oily solid
  3. customRecrystallization from ethanol

Quellen und Nachweise

ORD-Eintrag
ord-d8a37e776cf24f558a0f0ecd6e81495c
Quelldatensatz
uspto-grants-1984_10
Patentnummer
US04478992

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