Chlorosulfonic acid → 4-(3-Methyl-2-oxo-1-imidazolidinyl)benzenesulfonyl chloride

HRID 1634825Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1634825
[CH3:1][N:2]1[CH:6]=[CH:5][N:4]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[C:3]1=[O:13].[Cl:14][S:15](O)(=[O:17])=[O:16]>>[CH3:1][N:2]1[CH2:6][CH2:5][N:4]([C:7]2[CH:12]=[CH:11][C:10]([S:15]([Cl:14])(=[O:17])=[O:16])=[CH:9][CH:8]=2)[C:3]1=[O:13]

Komponenten

3

Edukt 2

HCID 24638Chlorosulfonic acidHCID 197983301,3-Dihydro-1-methyl-3-phenyl-2H-imidazol-2-one

Produkt 1

HCID 186784164-(3-Methyl-2-oxo-1-imidazolidinyl)benzenesulfonyl chloride

Versuchsvorschrift

A solution of 1-methyl-3-phenylimidazol-2-one (5.7 g, 32.3 mmol) in 10 mL of chlorosulfonic acid was stirred at ambient temperature for 30 minutes. The reaction mixture was poured into ice/water and extracted with ethyl acetate. The organic phase was separated, dried (Na2SO4) and concentrated in vacuo to a white solid (7.4 g). Used as is in the following prep.

Aufarbeitung

  1. extractionextracted with ethyl acetate
  2. customThe organic phase was separated
  3. dry with materialdried (Na2SO4)
  4. concentrationconcentrated in vacuo to a white solid (7.4 g)

Quellen und Nachweise

ORD-Eintrag
ord-f32be6f8ac794ae786cde1bc3dc3445f
Quelldatensatz
uspto-grants-2003_01
Patentnummer
US06506901B2

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