HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Ethyl 3-oxo-3-(thiophen-3-yl)propanoate → [3-(3-Oxo-3-thiophen-3-yl-propionylamino)-biphenyl-4-yl]-carbamic acid tert.-butyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Ethyl 3-oxo-3-(thiophen-3-yl)propanoate | HCID 10535956 | — |
| Edukt | N-(3-Amino[1,1'-biphenyl]-4-yl)-carbamic Acid tert-Butyl Ester | HCID 57717454 | — |
| Produkt | [3-(3-Oxo-3-thiophen-3-yl-propionylamino)-biphenyl-4-yl]-carbamic acid tert.-butyl ester | HCID 86588003 | 81,3% |
Reaktionsschritte
Prepared from (3-amino-biphenyl-4-yl)-carbamic acid tert.-butyl ester (Example G9) (144 mg, 0.51 mmol) and 3-oxo-3-thiophen-3-yl-propionic acid ethyl ester (FR 7191887) (151 mg, 0.76 mmol) according to the general procedure K. Obtained as a yellow foam (181 mg).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06509328B1 |
| Quelldatensatz | uspto-grants-2003_01 |
| ORD ID | ord-6223e84c510c41be8c20dddbb02c9297 |
| Quellennotiz | uspto-grants-2003_01 |