Acetyl chloride → HCID 54052838, Verbindung

HRID 1636308Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1636308
[C:1](Cl)(=[O:3])[CH3:2].[N:5]1[CH:10]=[CH:9][CH:8]=[C:7]([CH:11]=[N:12][N:13]2[CH:17]=[N:16][NH:15][C:14]2=[O:18])[CH:6]=1>N1C=CC=CC=1>[C:1]([N:15]1[C:14](=[O:18])[N:13]([N:12]=[CH:11][C:7]2[CH:6]=[N:5][CH:10]=[CH:9][CH:8]=2)[CH:17]=[N:16]1)(=[O:3])[CH3:2]

Komponenten

4

Edukt 2

HCID 6367Acetyl chlorideHCID 54560653HCID 54560653, Verbindung

Produkt 1

HCID 54052838HCID 54052838, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1049PyridineLösungsmittel

Versuchsvorschrift

2.4 g of acetyl chloride are added to a suspension of 3.8 g of 4-(pyridin-3-ylmethyleneamino)-1,2,4-triazol-3-one in 50 ml of pyridine. The resulting solution is stirred for 14 hours at 20° and then concentrated by evaporation. Water is added to the residue and extraction is carried out with chloroform. The organic phase is concentrated by evaporation and the residue is stirred with ether. The crystals are filtered off with suction and then dried under a high vacuum. 4 g of the title compound having a melting point of 164-166° are thus obtained.

Aufarbeitung

  1. concentrationconcentrated by evaporation
  2. additionWater is added to the residue and extraction
  3. concentrationThe organic phase is concentrated by evaporation
  4. stirringthe residue is stirred with ether
  5. filtrationThe crystals are filtered off with suction
  6. customdried under a high vacuum
  7. customare thus obtained

Quellen und Nachweise

ORD-Eintrag
ord-8ba73ba7b69b4cc1ad066b02c4331657
Quelldatensatz
uspto-grants-2000_03
Patentnummer
US06034083

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