Ethylenediamine → HCID 18783142, Verbindung

HRID 1636456Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1636456
[CH3:1][C:2]1([CH3:11])[CH2:7][C:6]([CH3:9])([CH3:8])[CH2:5][C:4](=O)[CH2:3]1.C(N)CN.[N+:16]([CH3:19])([O-:18])=[O:17]>>[N+:16]([CH2:19][C:4]1[CH2:3][C:2]([CH3:11])([CH3:1])[CH2:7][C:6]([CH3:9])([CH3:8])[CH:5]=1)([O-:18])=[O:17]

Komponenten

4

Edukt 3

HCID 3301EthylenediamineHCID 6375NitromethaneHCID 843993,3,5,5-Tetramethylcyclohexanone

Produkt 1

HCID 18783142HCID 18783142, VerbindungAusbeute 61 %

Versuchsvorschrift

A solution of 3,3,5,5-tetramethylcyclohexanone (2-13) (1.54 g, 10 mmol) and ethylenediamine (60 mg) in nitromethane (45 ml) was refluxed in argon atmosphere for 25 h. Excess of nitromethane was then removed in vacuo and the residue was purified by flash chromatography on silica gel, eluting with hexane--ethyl acetate (6:1). 1.2 g (61%) of 6 was obtained as an oil.

Aufarbeitung

  1. customExcess of nitromethane was then removed in vacuo
  2. customthe residue was purified by flash chromatography on silica gel
  3. washeluting with hexane--ethyl acetate (6:1)

Quellen und Nachweise

ORD-Eintrag
ord-65643282abb34c6b90532121dd8edec0
Quelldatensatz
uspto-grants-2000_03
Patentnummer
US06034134

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