Ammonia → Ammonium 4-(benzothiazol-2-yl)phenylsulphamate

HRID 1636567

Reaktionsgleichung

Reaktionsgleichung von HRID 1636567
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[S:9][C:10]3[CH:16]=[CH:15][CH:14]=[CH:13][C:11]=3[N:12]=2)=[CH:4][CH:3]=1.Cl[S:18]([OH:21])(=[O:20])=[O:19].S(=O)(=O)([O-])[NH2:23].N>N1C=CC=CC=1C>[S:9]1[C:10]2[CH:16]=[CH:15][CH:14]=[CH:13][C:11]=2[N:12]=[C:8]1[C:5]1[CH:4]=[CH:3][C:2]([NH:1][S:18](=[O:20])(=[O:19])[O-:21])=[CH:7][CH:6]=1.[NH4+:23]

Komponenten

6

Edukt 4

HCID 222AmmoniaHCID 24638Chlorosulfonic acidHCID 177700Sulfamate ionHCID 2344752-(4-Aminophenyl)benzothiazole

Produkt 1

HCID 19352177Ammonium 4-(benzothiazol-2-yl)phenylsulphamateAusbeute 69 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 79752-MethylpyridineLösungsmittel

Versuchsvorschrift

2(4'-Aminophenyl)benzothiazole was treated with chlorsulphonic acid in 2-picoline according to the above-described general procedure for preparation of sulphamate salts. About 35% ammonia solution instead of 10% aqueous Na2CO3 was used. A yellow powder was afforded in 69% yield, m.p. 223.1-226.8° C.

Aufarbeitung

  1. customA yellow powder was afforded in 69% yield, m.p. 223.1-226.8° C.

Quellen und Nachweise

ORD-Eintrag
ord-6b07ca4566c54136a4afba5318b974d9
Quelldatensatz
uspto-grants-2000_03
Patentnummer
US06034246

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