5-(3-Iodophenyl)-3-methyl-1,2,4-oxadiazole → (S)-methyl-3-(3-cyclopentyloxy-4-methoxyphenyl)-5-[3-(3-methyl[1,2,4]oxadiazol-5-yl)phenyl]pent-4ynoate
Reaktionsgleichung
[CH3:1][O:2][C:3](=[O:22])[CH2:4][C@@H:5]([C:8]1[CH:13]=[CH:12][C:11]([O:14][CH3:15])=[C:10]([O:16][CH:17]2[CH2:21][CH2:20][CH2:19][CH2:18]2)[CH:9]=1)[C:6]#[CH:7].[CH3:23][C:24]1[N:28]=[C:27]([C:29]2[CH:30]=[C:31](I)[CH:32]=[CH:33][CH:34]=2)[O:26][N:25]=1>CCN(CC)CC.C1C=CC([P]([Pd]([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)[P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)=CC=1.[Cu]I>[CH3:1][O:2][C:3](=[O:22])[CH2:4][C@@H:5]([C:8]1[CH:13]=[CH:12][C:11]([O:14][CH3:15])=[C:10]([O:16][CH:17]2[CH2:21][CH2:20][CH2:19][CH2:18]2)[CH:9]=1)[C:6]#[C:7][C:31]1[CH:32]=[CH:33][CH:34]=[C:29]([C:27]2[O:26][N:25]=[C:24]([CH3:23])[N:28]=2)[CH:30]=1Komponenten
6
