Isobutyramide → Diisopropyl Ether

HRID 1637462

Reaktionsgleichung

Reaktionsgleichung von HRID 1637462
[CH3:1][CH:2]([CH3:6])[C:3]([NH2:5])=[O:4].[C:7]([C:11]1[CH:16]=[CH:15][C:14]([C:17]([OH:19])=O)=[CH:13][C:12]=1[NH:20][C:21](=[O:38])[CH2:22][CH:23]([C:28]1[CH:33]=[CH:32][C:31]([O:34][CH3:35])=[CH:30][C:29]=1[O:36][CH3:37])[CH2:24][CH2:25][CH2:26][CH3:27])([CH3:10])([CH3:9])[CH3:8]>>[C:7]([C:11]1[CH:16]=[CH:15][C:14]([C:17]([NH:5][C:3](=[O:4])[CH:2]([CH3:6])[CH3:1])=[O:19])=[CH:13][C:12]=1[NH:20][C:21](=[O:38])[CH2:22][CH:23]([C:28]1[CH:33]=[CH:32][C:31]([O:34][CH3:35])=[CH:30][C:29]=1[O:36][CH3:37])[CH2:24][CH2:25][CH2:26][CH3:27])([CH3:8])([CH3:9])[CH3:10].[CH:31]([O:34][CH:2]([CH3:3])[CH3:6])([CH3:32])[CH3:30]

Komponenten

4

Edukt 2

HCID 68424IsobutyramideHCID 19348750N-(2-t-butyl-5-carboxyphenyl)-3-(2,4-dimethoxyphenyl)heptanamide

Produkt 2

HCID 7914Diisopropyl EtherHCID 19348690N-[2-t-Butyl-5-(2-methylpropanoyl)aminocarbonylphenyl]-3-(2,4-dimethoxyphenyl)heptanamide

Versuchsvorschrift

Following a similar procedure to that described in Example 139, but using 2-methylpropanamide and N-(2-t-butyl-5-carboxyphenyl)-3-(2,4-dimethoxyphenyl)heptanamide (prepared as described in Preparation 31B), the title compound was obtained as crystals, melting at 139-140° C. (from diisopropyl ether).

Quellen und Nachweise

ORD-Eintrag
ord-4a2ed6b94c9842d69d5b235abc161389
Quelldatensatz
uspto-grants-2000_03
Patentnummer
US06040339

Verknüpfte Notizen

Wird geladen…