Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Nitric Acid | HCID 944 | — |
| Edukt | Sodium Bicarbonate | HCID 516892 | — |
| Edukt | 5H-Pyrrolo[2,3-b]pyrazine | HCID 5370803 | — |
| Lösungsmittel | Water | HCID 962 | — |
| Produkt | 7-nitro-5H-pyrrolo[2,3-b]pyrazine | HCID 12207192 | — |
Reaktionsschritte
7-Nitro-5H-pyrrolo[2,3-b]pyrazine (5) is prepared by adding 5H-pyrrolo[2,3-b]pyrazine (3) to fuming nitric acid while cooling (e.g. 0° C.). After stirring for one to several hours, water is carefully added and the mixture neutralized with saturated sodium bicarbonate. The solids are collected by filtration and dried to provide 7-nitro-5H-pyrrolo[2,3-b]pyrazine 5.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patentnummer | US08119637B2 |
|---|
| Quelldatensatz | uspto-grants-2012_02 |
|---|
| ORD ID | ord-154cf4acfdd640b3a18fb50da19058f6 |
|---|
| Quellennotiz | uspto-grants-2012_02 |
|---|
