HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
N-Hydroxy-2-methyl-benzamidine → HCID 58002717, Verbindung
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | N-Hydroxy-2-methyl-benzamidine | HCID 3098087 | — |
| Edukt | 1-(Morpholin-4-ylcarbonyl)-5-[4-(trifluoromethoxy)phenyl]piperidine-3-carboxylic acid | HCID 58002500 | — |
| Produkt | HCID 58002717 | HCID 58002717 | — |
Reaktionsschritte
80 mg (0.20 mmol) of 1-(morpholin-4-ylcarbonyl)-5-[4-(trifluoromethoxy)phenyl]piperidine-3-carboxylic acid (Example 44A) and 33 mg (0.22 mmol, 1.1 eq.) of N′-hydroxy-2-methylbenzenecarboximidamide were reacted according to the General Method 1. Yield: 14 mg (13% of theory)
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08119663B2 |
| Quelldatensatz | uspto-grants-2012_02 |
| ORD ID | ord-d36dcf5603ef401cac96f20575544967 |
| Quellennotiz | uspto-grants-2012_02 |