N'-hydroxycyclobutanecarboximidamide → HCID 58002712, Verbindung
Reaktionsgleichung
[N:1]1([C:7]([N:9]2[CH2:14][CH:13]([C:15]3[CH:20]=[CH:19][C:18]([C:21]([F:24])([F:23])[F:22])=[CH:17][CH:16]=3)[CH2:12][CH:11]([C:25](O)=[O:26])[CH2:10]2)=[O:8])[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.O[N:29]=[C:30]([CH:32]1[CH2:35][CH2:34][CH2:33]1)[NH2:31]>>[CH:32]1([C:30]2[N:31]=[C:25]([CH:11]3[CH2:12][CH:13]([C:15]4[CH:20]=[CH:19][C:18]([C:21]([F:24])([F:23])[F:22])=[CH:17][CH:16]=4)[CH2:14][N:9]([C:7]([N:1]4[CH2:2][CH2:3][O:4][CH2:5][CH2:6]4)=[O:8])[CH2:10]3)[O:26][N:29]=2)[CH2:35][CH2:34][CH2:33]1Komponenten
3
Versuchsvorschrift
150 mg (0.388 mmol) of the compound from Example 81A and 88 mg (0.776 mmol) of N′-hydroxycyclobutanecarboximidamide were reacted according to the General Method 2. Yield: 124 mg (65% of theory)
Quellen und Nachweise
- ORD-Eintrag
- ord-c54d4a8745164ee1bc90b7e645f4336d
- Quelldatensatz
- uspto-grants-2012_02