HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-Amino-N-methylbenzamide → 4-chloro-3-(trifluoromethyl)phenyl-N'-(4-(3-methylcarbamoylphenyl)carbamoylphenyl) urea
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-Amino-N-methylbenzamide | HCID 676526 | — |
| Edukt | 4-Chloro-3-(trifluoromethyl)phenyl-N'-(4-carboxyphenyl)urea | HCID 23614596 | — |
| Produkt | 4-chloro-3-(trifluoromethyl)phenyl-N'-(4-(3-methylcarbamoylphenyl)carbamoylphenyl) urea | HCID 23614591 | — |
Reaktionsschritte
Entry 67: N-(4-Chloro-3-(trifluoromethyl)phenyl-N′-(4-ethoxycarbonylphenyl) urea was synthesized according to Method C1e. N-(4-Chloro-3-(trifluoromethyl)phenyl-N′-(4-ethoxycarbonylphenyl) urea was saponified according to Method D3 to give N-(4-chloro-3-(trifluoromethyl)phenyl-N′-(4-carboxyphenyl) urea. N-(4-Chloro-3-(trifluoromethyl)phenyl-N′-(4-carboxyphenyl) urea was coupled with 3-methylcarbamoylaniline according to Method D1b to give N-(4-chloro-3-(trifluoromethyl)phenyl-N′-(4-(3-methylcarbamoylphenyl)carbamoylphenyl) urea.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08124630B2 |
| Quelldatensatz | uspto-grants-2012_02 |
| ORD ID | ord-82e11c05c9f84429ad82740821a6daec |
| Quellennotiz | uspto-grants-2012_02 |