Furfural → HCID 178447403, Verbindung
Reaktionsgleichung
FC(F)(F)C(O)=O.[NH2:8][C:9]([CH3:45])([CH3:44])[CH2:10][C:11]([NH:13][C@H:14]1[C:20](=[O:21])[N:19]([CH2:22][C:23]2[CH:28]=[CH:27][C:26]([C:29]3[CH:34]=[CH:33][CH:32]=[CH:31][C:30]=3[C:35]3[NH:39][N:38]=[N:37][N:36]=3)=[CH:25][CH:24]=2)[C:18]2[CH:40]=[CH:41][CH:42]=[CH:43][C:17]=2[S:16][CH2:15]1)=[O:12].[CH:46](=O)[C:47]1[O:51][CH:50]=[CH:49][CH:48]=1>>[O:51]1[CH:50]=[CH:49][CH:48]=[C:47]1[CH2:46][NH:8][C:9]([CH3:45])([CH3:44])[CH2:10][C:11]([NH:13][C@H:14]1[C:20](=[O:21])[N:19]([CH2:22][C:23]2[CH:24]=[CH:25][C:26]([C:29]3[CH:34]=[CH:33][CH:32]=[CH:31][C:30]=3[C:35]3[NH:39][N:38]=[N:37][N:36]=3)=[CH:27][CH:28]=2)[C:18]2[CH:40]=[CH:41][CH:42]=[CH:43][C:17]=2[S:16][CH2:15]1)=[O:12]Komponenten
3
Versuchsvorschrift
The title compound is prepared from 3-amino-3-methyl-N-[3,4-dihydro-4-oxo-5-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1,5-benzothiazepin-3(S)-yl]butanamide trifluoroacetate (prepared by the method of M. Fisher, et al, U.S. Pat. No. 5,206,235) and furfuraldehyde by the procedures described in Example 1.
Aufarbeitung
- customprepared by the method of M
Quellen und Nachweise
- ORD-Eintrag
- ord-98f164d2964e440fb6788194969cb1bc