HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Trifluoroacetic acid → 4,6-Bis (1,1-dimethylethyl)-5-hydroxy-2-pyrimidine carbonitrile
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Trifluoroacetic acid | HCID 6422 | — |
| Edukt | 4,6-Bis(1,1-dimethylethyl)-5-[(2-methoxyethoxy)-methoxy]-2-pyrimidinecarbonitrile | HCID 19922986 | — |
| Produkt | 4,6-Bis (1,1-dimethylethyl)-5-hydroxy-2-pyrimidine carbonitrile | HCID 15294897 | 68,2% |
Reaktionsschritte
According to the procedure of Example 18, 4,6-bis(1,1-dimethylethyl) -5-[(2-methoxyethoxy)methoxy]-2-pyrimidine carbonitrile (9.1 g, 28.3 mmol) is treated with trifluoroacetic acid to give 4,6-bis(1,1-dimethylethyl)-5-hydroxy-2-pyrimidine carbonitrile (4.5 g, 68%); mp 203°-205° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05432181 |
| Quelldatensatz | uspto-grants-1995_07 |
| ORD ID | ord-c489861f71f146a69ac58151c26e9de4 |
| Quellennotiz | uspto-grants-1995_07 |