Ethyl propiolate → Bis[1-(beta-ethoxycarbonylvinyl)-2,2,6,6-tetramethyl-4-piperidinyl] malonate

HRID 1647867

Reaktionsgleichung

Reaktionsgleichung von HRID 1647867
[C:1]([O:5][CH2:6][CH3:7])(=[O:4])[C:2]#[CH:3].[C:8]([O:24][CH:25]1[CH2:30][C:29]([CH3:32])([CH3:31])[NH:28][C:27]([CH3:34])([CH3:33])[CH2:26]1)(=[O:23])[CH2:9][C:10]([O:12][CH:13]1[CH2:18][C:17]([CH3:20])([CH3:19])[NH:16][C:15]([CH3:22])([CH3:21])[CH2:14]1)=[O:11]>C(O)C>[C:8]([O:24][CH:25]1[CH2:30][C:29]([CH3:32])([CH3:31])[N:28]([CH:3]=[CH:2][C:1]([O:5][CH2:6][CH3:7])=[O:4])[C:27]([CH3:34])([CH3:33])[CH2:26]1)(=[O:23])[CH2:9][C:10]([O:12][CH:13]1[CH2:18][C:17]([CH3:20])([CH3:19])[N:16]([CH:3]=[CH:2][C:1]([O:5][CH2:6][CH3:7])=[O:4])[C:15]([CH3:22])([CH3:21])[CH2:14]1)=[O:11]

Komponenten

4

Edukt 2

HCID 12182Ethyl propiolateHCID 1244568Bis(2,2,6,6-tetramethylpiperidin-4-yl) propanedioate

Produkt 1

HCID 67781170Bis[1-(beta-ethoxycarbonylvinyl)-2,2,6,6-tetramethyl-4-piperidinyl] malonateAusbeute 60 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

150 g of ethyl propiolate were added dropwise to a solution of 270 g of bis(2,2,6,6-tetramethyl-4-piperidinyl) malonate in 400 ml of ethanol at 60° C. The mixture was then refluxed for 4 hours. The solvent was removed by distillation under reduced pressure, and recrystallization of the resulting residue from isopropanol yielded 245 g of the compound of the formula shown below in the form of a colorless solid of melting point 100°-102° C. ##STR23##

Aufarbeitung

  1. temperatureThe mixture was then refluxed for 4 hours
  2. customThe solvent was removed by distillation under reduced pressure, and recrystallization of the resulting residue from isopropanol

Quellen und Nachweise

ORD-Eintrag
ord-c04a83608d9a411484b2b9b0c79b63c8
Quelldatensatz
uspto-grants-1995_07
Patentnummer
US05434202

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