2,2,6-Trimethyl-5-phenyl-2H,4H-1,3-dioxin-4-one → 6-methyl-3-[1-methyl-1-(2naphthyl)ethyl]-5-phenyl-2,3-dihydro-4H-1,3-oxazin-4-one

HRID 1648198Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1648198
[C:1]1([C:7]2[C:8](=[O:16])O[C:10](C)(C)[O:11][C:12]=2[CH3:13])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C=[N:18][C:19]([CH3:31])([C:21]1[CH:30]=[CH:29][C:28]2[C:23](=[CH:24][CH:25]=[CH:26][CH:27]=2)[CH:22]=1)[CH3:20]>C1(C)C(C)=CC=CC=1>[CH3:13][C:12]1[O:11][CH2:10][N:18]([C:19]([CH3:31])([C:21]2[CH:30]=[CH:29][C:28]3[C:23](=[CH:24][CH:25]=[CH:26][CH:27]=3)[CH:22]=2)[CH3:20])[C:8](=[O:16])[C:7]=1[C:1]1[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Komponenten

4

Edukt 2

HCID 131570242,2,6-Trimethyl-5-phenyl-2H,4H-1,3-dioxin-4-oneHCID 19918961N-methylene-1-methyl-1-(2-naphthyl)ethylamine

Produkt 1

HCID 199189456-methyl-3-[1-methyl-1-(2naphthyl)ethyl]-5-phenyl-2,3-dihydro-4H-1,3-oxazin-4-oneAusbeute 37,6 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 7237O-XyleneLösungsmittel

Versuchsvorschrift

A mixture of 5-phenyl-2,2,6-trimethyl-2H,4H-1,3-dioxin-4-one (0.65 g), N-methylene-1-methyl-1-(2-naphthyl)ethylamine (0.60 g) and xylene (3 ml) was heated at reflux for 20 minutes for reaction. The reaction mixture was purified by silica gel chromatography to obtain the captioned compound (0.40 g).

Aufarbeitung

  1. temperaturewas heated
  2. temperatureat reflux for 20 minutes for reaction
  3. customThe reaction mixture was purified by silica gel chromatography

Quellen und Nachweise

ORD-Eintrag
ord-f7ad375ac89c4f4a9bdacd01dd5e2fdb
Quelldatensatz
uspto-grants-1995_07
Patentnummer
US05436224

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