1-(1H-indol-3-yl)-2-methylpropan-2-amine → [2-(1H-indol-3-yl)-1,1-dimethylethyl]{-[2-(2-methylprop-1-yloxy)phenoxy]ethyl}amine hydrochloride

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	1-(1H-indol-3-yl)-2-methylpropan-2-amine	HCID 9353	—
Edukt	5-Chloro-alpha,alpha-dimethyl-1H-indole-3-ethanamine	HCID 13260	—
Edukt	2-[2-(2-Methylprop-1-yloxy)phenoxy]ethyl methanesulfonate	HCID 15289997	—
Produkt	[2-(1H-indol-3-yl)-1,1-dimethylethyl]{-[2-(2-methylprop-1-yloxy)phenoxy]ethyl}amine hydrochloride	HCID 19919953	—

Reaktionsschritte

Proceeding as an Example 3, but replacing 2-[2-(cyclopropylmethyloxy)phenoxy]ethyl methanesulfonate with 2-[2-(2-methylprop-1-yloxy)phenoxy]ethyl methanesulfonate and [2-(5-chloro-1H-indol-3-yl)-1,1-dimethylethyl]amine with [2- (1H-indol-3-yl)-1,1-dimethylethyl]amine, gave [2-(1H-indol-3-yl)-1,1-dimethylethyl]{-[2-(2-methylprop-1-yloxy)phenoxy]ethyl}amine hydrochloride, m.p. 147°-148° C.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US05436264
Quelldatensatz	uspto-grants-1995_07
ORD ID	ord-82c864aed14a4276955dd18dbaccb624
Quellennotiz	uspto-grants-1995_07