Thionyl Chloride → 7,8-Dihydroxychromone-3-carbonyl chloride

HRID 1649126Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1649126
[OH:1][C:2]1[C:11]([OH:12])=[C:10]2[C:5]([C:6](=[O:16])[C:7]([C:13](O)=[O:14])=[CH:8][O:9]2)=[CH:4][CH:3]=1.S(Cl)([Cl:19])=O>>[OH:1][C:2]1[C:11]([OH:12])=[C:10]2[C:5]([C:6](=[O:16])[C:7]([C:13]([Cl:19])=[O:14])=[CH:8][O:9]2)=[CH:4][CH:3]=1

Komponenten

3

Edukt 2

HCID 24386Thionyl Chloride2×HCID 127658447,8-Dihydroxychromone-3-carboxylic acid

Produkt 1

HCID 130830427,8-Dihydroxychromone-3-carbonyl chloride

Versuchsvorschrift

7,8-Dihydroxychromone-3-carboxylic acid (6.6 g) together with thionyl chloride (25 ml) were refluxed for one hour. Certain unreacted thionyl chloride remained in the reaction mixture was distilled off, and after addition of benzene to the residue, the mixture was again subjected to distillation. To the residue was added n-hexane to cause trituration of the residue. The solid matter thus formed was recovered by filtration. There was thus obtained the desired product (7.2 g).

Aufarbeitung

  1. distillationwas distilled off
  2. additionafter addition of benzene to the residue
  3. distillationthe mixture was again subjected to distillation
  4. additionTo the residue was added n-hexane
  5. customThe solid matter thus formed
  6. filtrationwas recovered by filtration

Quellen und Nachweise

ORD-Eintrag
ord-817e109aab524326bc5990cc5a6b7c94
Quelldatensatz
uspto-grants-1983_11
Patentnummer
US04415567

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