Sodium Hydroxide → HCID 14304543, Verbindung

HRID 1649958Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1649958
[CH3:1][O:2][C:3]1[CH:23]=[CH:22][C:6]([C:7]([C:9]2[CH:20]=[CH:19][C:12]([O:13][CH2:14][C:15]([O:17]C)=[O:16])=[C:11]([CH3:21])[CH:10]=2)=[O:8])=[CH:5][CH:4]=1.[OH-].[Na+]>O1CCOCC1>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([C:7]([C:9]2[CH:20]=[CH:19][C:12]([O:13][CH2:14][C:15]([OH:17])=[O:16])=[C:11]([CH3:21])[CH:10]=2)=[O:8])=[CH:22][CH:23]=1

Komponenten

4

Edukt 2

HCID 14798Sodium HydroxideHCID 13966816Methyl [4-(4-methoxybenzoyl)-2-methylphenoxy]acetate

Produkt 1

HCID 14304543HCID 14304543, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 312751,4-DioxaneLösungsmittel

Versuchsvorschrift

35.8 g of methyl 4-(4-methoxybenzoyl)-2-methylphenoxyacetate are stirred with a mixture of 240 ml of dioxane and 240 ml of 0.5N NaOH at room temperature. After the reaction is complete, the organic solvent is removed in vacuo, and the aqueous phase is adjusted to pH 3 with 2N HCl and extracted with ethyl acetate. The organic phase is washed with water, dried over magnesium sulfate and concentrated. Pale yellow crystals remain.

Aufarbeitung

  1. customthe organic solvent is removed in vacuo
  2. extractionextracted with ethyl acetate
  3. washThe organic phase is washed with water
  4. dry with materialdried over magnesium sulfate
  5. concentrationconcentrated

Quellen und Nachweise

ORD-Eintrag
ord-88813c6be48e4e3dbf0f8effcfe2495e
Quelldatensatz
uspto-grants-1990_05
Patentnummer
US04922015

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