Boron trifluoride etherate → Ethyl 4-(mercaptomethyl)-2-methyl-1,3-dithiolane-2-propanoate

HRID 1650248Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1650248
[SH:1][CH2:2][CH:3]([SH:6])[CH2:4][SH:5].[C:7]([O:14][CH2:15][CH3:16])(=[O:13])[CH2:8][CH2:9][C:10]([CH3:12])=O.B(F)(F)F.CCOCC>C(Cl)Cl>[SH:1][CH2:2][CH:3]1[CH2:4][S:5][C:10]([CH3:12])([CH2:9][CH2:8][C:7]([O:14][CH2:15][CH3:16])=[O:13])[S:6]1

Komponenten

5

Edukt 3

HCID 8000Boron trifluoride etherateHCID 10883Ethyl levulinateHCID 784951,2,3-Propanetrithiol

Produkt 1

HCID 14405950Ethyl 4-(mercaptomethyl)-2-methyl-1,3-dithiolane-2-propanoate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

The title compound was prepared according to the procedure of Example 1 using 1,2,3-trimercaptopropane (5.6 g, 0.04 mol), ethyl levulinate (5.8 g, 0.04 mol) and boron trifluoride etherate (1.25 ml) in methylene chloride (150 ml). The crude product was chromatographed on silica gel using 5% ethyl acetate/hexane as eluent to give 3.35 g (31%) of product.

Aufarbeitung

  1. customThe crude product was chromatographed on silica gel using 5% ethyl acetate/hexane as eluent

Quellen und Nachweise

ORD-Eintrag
ord-7cc069acdfad4109be4f3cc6cd629c36
Quelldatensatz
uspto-grants-1990_05
Patentnummer
US04923891

Notizen zur Reaktion

Wird geladen…