4-Dodecyloxy-2-chlorobenzoic acid → 4-Dodecyloxy-2-chlorobenzyl alcohol
Reaktionsgleichung
[CH2:1]([O:13][C:14]1[CH:22]=[CH:21][C:17]([C:18](O)=[O:19])=[C:16]([Cl:23])[CH:15]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].[H-].[H-].[H-].[H-].[Li+].[Al+3]>>[CH2:1]([O:13][C:14]1[CH:22]=[CH:21][C:17]([CH2:18][OH:19])=[C:16]([Cl:23])[CH:15]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12]Komponenten
3
Versuchsvorschrift
According to customary procedures, 4-dodecyloxy-2-chlorobenzoic acid synthesized in the same manner as described in Referential Example 15 was reduced with LiAlH4 to obtain 4-dodecyloxy-2-chlorobenzyl alcohol, and this compound was brominated with PBr3 to obtain 4-dodecyloxy-2-chlorobenzyl bromide. In the same manner as described in Referential Example 18, 2.0 g of the so-obtained compound was reacted with 1.0 g of 4-acetoxyphenol to obtain 4-dodecyloxy-2-chlorobenzyl(4-acetoxyphenyl) ether. Then, the acetyl group was removed by an equimolar amount of LiOH, whereby 0.9 g of 4-dodecyloxy-2-chlorobenzyl(4-hydroxyphenyl) ether was obtained.
Aufarbeitung
- customsynthesized in the same manner