Fumarate → 5-Methyl-2-(1-methyl-1,2,5,6-tetrahydro-3-pyridyl)-thiazole

HRID 1650706Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1650706
[CH3:1][C:2]1[S:6][C:5]([C:7]2[CH:8]=[N:9][CH:10]=[CH:11][CH:12]=2)=[N:4][CH:3]=1.[C:13]([O-])(=O)/C=C/C([O-])=O>>[CH3:1][C:2]1[S:6][C:5]([C:7]2[CH2:8][N:9]([CH3:13])[CH2:10][CH2:11][CH:12]=2)=[N:4][CH:3]=1

Komponenten

3

Edukt 2

HCID 5460307FumarateHCID 196125135-Methyl-2-(3-pyridyl)-thiazole

Produkt 1

HCID 196124795-Methyl-2-(1-methyl-1,2,5,6-tetrahydro-3-pyridyl)-thiazole

Versuchsvorschrift

The title compound was prepared from 88 (2.2 g, 0.013 mol) by the procedure described in Example 49. The crude free base obtained, 89, was converted to the title fumarate, 90. Yield: 0.8 g (0.0032 mol, 25%). M.P. 159°-160° C. Anal. (C12H16N2O2S) C, H, N.

Aufarbeitung

  1. customThe crude free base obtained

Quellen und Nachweise

ORD-Eintrag
ord-a0a7b3624597440d8520434a7d90b91e
Quelldatensatz
uspto-grants-1990_05
Patentnummer
US04925858

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