Hydrogen Sulfide → 1-phenyl-2-sulfanylethan-1-ol

Temperatur

100 °C

1-mercapto-2-phenyl-2-ethanol was prepared from 1000 grams of styrene oxide, 567 grams of H2S and 10 mL of a 20 weight % NaOH solution in methanol. These reactants were pumped into a 1 gallon autoclave reactor and heated from 28° C. to 59° C. during a 1-hour period while the pressure rose from about 350 psig to about 500 psig. At the end of the 1-hour period an additional 20 mL of the NaOH in methanol solution was charged to the autoclave and the reaction mixture was reheated to about 60° C. (at 490 psig) during a 2 hour period. Thereafter, 50 mL of the NaOH/methanol solution was charged to the autoclave and the entire reaction mixture was heated to about 100° C. (at 490 psig) during a period of 50 minutes. Then 50 mL of methanol was added to the autoclave and heating at about 100° C. (400 psig) continued for about 1 hour. 1353 grams of the product, 1-mercapto-2-phenyl-2-ethanol, were recovered.

1. customThese reactants were pumped into a 1 gallon autoclave reactor
2. temperatureheated from 28° C. to 59° C. during a 1-hour period while the pressure
3. customwas reheated to about 60° C.
4. customduring a 2 hour
5. customthe entire reaction mixture
6. temperatureheating at about 100° C. (400 psig)
7. custom1353 grams of the product, 1-mercapto-2-phenyl-2-ethanol, were recovered

ORD-Eintrag

ord-dacbe93bef51491aa5e654c412039e62

Quelldatensatz

uspto-grants-1995_04

DOI

10.6084/m9.figshare.5104873.v1

Patentnummer

US05403502