HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Aminoindane → (1H-Benzoimidazol-2-yl)indan-2-ylamine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-Aminoindane | HCID 76310 | — |
| Edukt | 2-Chlorobenzimidazole | HCID 78572 | — |
| Produkt | (1H-Benzoimidazol-2-yl)indan-2-ylamine | HCID 11658857 | — |
Reaktionsschritte
The title compound was prepared from 2-chlorobenzimidazole and 2-aminoindane by Procedure A (15 min at 150° C.). The product was isolated by preparative LCMS to give the title compound as the free base (white solid, mp 246-249° C.). MS(ES+) m/z 250 ([M+1]+, 100). 1NMR (DMSO-d6) δ 2.91 (dd, 2H), 3.29 (dd, 2H), 4.35 (m, 1H), 6.80-6.92 (m, 3H), 7.10-7.17 (m, 4H), 7.22-7.25 (m, 2H), 10.60 (s, 1H).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07737167B2 |
| Quelldatensatz | uspto-grants-2010_06 |
| ORD ID | ord-94593ddfd76d49909c5e0097ba1ae034 |
| Quellennotiz | uspto-grants-2010_06 |