HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Toluene → 3-(2,4,6-Trifluorobenzyloxy)pyrid-2-yl-N'-(4-chlorophenyl)thiourea
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Toluene | HCID 1140 | — |
| Edukt | 4-Chlorophenyl isothiocyanate | HCID 16480 | — |
| Edukt | 2-Amino-3-(2,4,6-trifluorobenzyloxy)pyridine | HCID 10015161 | — |
| Lösungsmittel | Diethyl Ether | HCID 3283 | — |
| Produkt | 3-(2,4,6-Trifluorobenzyloxy)pyrid-2-yl-N'-(4-chlorophenyl)thiourea | HCID 20077009 | — |
Reaktionsschritte
A mixture of 2-amino-3-(2,4,6-trifluorobenzyloxy)pyridine (2.29 g, 0.009 mol), 4chlorophenyl isothiocyanate (1.81 g, 0.01 mol) and toluene (10 ml) was refluxed for 3.5 hours, then cooled and treated with diethyl ether to induce crystallisation of the product. Yield 3.03 g (79.5%), m.p.181°-183 ° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05409943 |
| Quelldatensatz | uspto-grants-1995_04 |
| ORD ID | ord-2c38946663564af9b9e2c72d913ca0cc |
| Quellennotiz | uspto-grants-1995_04 |