Ethyl Acetate → HCID 178488162, Verbindung
Reaktionsgleichung
[CH3:1][N:2]([CH3:24])[C:3]1[C:8](C)=[CH:7][N:6]=[C:5]([CH2:10][S:11][C:12]2[NH:16][C:15]3[CH:17]=[CH:18][C:19]([O:21][CH3:22])=[CH:20][C:14]=3[N:13]=2)[C:4]=1[Cl:23].C(OCC)(=[O:27])C>>[CH3:1][N:2]([CH3:24])[C:3]1[CH:8]=[CH:7][N:6]=[C:5]([CH2:10][S:11]([C:12]2[NH:16][C:15]3[CH:17]=[CH:18][C:19]([O:21][CH3:22])=[CH:20][C:14]=3[N:13]=2)=[O:27])[C:4]=1[Cl:23]Komponenten
3
Versuchsvorschrift
Substituting 2-(4-dimethylamino-3-chloro-2-pyridylmethylthio)-5-methoxy-(1H)-benzimidazole (3.43 g) for 2-(4-dimethylamino-3-chloro-5-methyl-2-pyridylmethylthio)-5-methoxy-(1H)-benzimidazole and using corresponding molar proportions of the other reagents in the method of Example 16, gave 2-(4-dimethylamino-3-chloro-2-pyridylmethylsulphinyl)-5-methoxy-(1H)-benzimidazole, (0.83 g), m.p. 113°-114° from ethyl acetate.
Quellen und Nachweise
- ORD-Eintrag
- ord-6a02e3f507aa434bb0bc9a600b5ae158
- Quelldatensatz
- uspto-grants-1993_10