Indole → HCID 19791527, Verbindung
Reaktionsgleichung
Cl.[CH:2]12[NH:10][CH:6]([CH2:7][CH2:8][CH2:9]1)[CH2:5][C:4](=O)[CH2:3]2.[F:12]C1C=CC(NN)=CC=1.[NH:21]1[C:29]2[C:24](=[CH:25][CH:26]=[CH:27][CH:28]=2)C=C1>C(Cl)Cl>[F:12][N:21]1[C:29]2[C:24](=[CH:25][CH:26]=[CH:27][CH:28]=2)[C:3]2[CH:2]3[NH:10][CH:6]([CH2:5][C:4]1=2)[CH2:7][CH2:8][CH2:9]3Komponenten
5
Edukt 3
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
This compound was prepared from 9-azabicyclo[3.3.1]nonan-3-one hydrochloride and 4-fluorophenylhydrazine by the Fischer indole synthesis as described in Example 1, Method A. The product was obtained as yellow crystals (74% yield), mp 200°-201° C. (from methylene chloride).
Quellen und Nachweise
- ORD-Eintrag
- ord-54fda50e2a9a46aab7bda45e782e2c64
- Quelldatensatz
- uspto-grants-1993_10
- Patentnummer
- US05250537
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