3-Cyanopyridine → N-(pyridin-3-ylmethyl)aniline
Reaktionsgleichung
[C:1]([C:3]1[CH:4]=[N:5][CH:6]=[CH:7][CH:8]=1)#[N:2].N[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1.[H][H]>[Rh]>[C:10]1([NH:2][CH2:1][C:3]2[CH:4]=[N:5][CH:6]=[CH:7][CH:8]=2)[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1Komponenten
5
Edukt 3
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
A mixture of 3-cyanopyridine (10.4 g), aniline (101.8 g) and a 5% rhodium on carbon catalyst (1.0 g) was treated with hydrogen at 60 psig 30 deg C. for 13 hours in a rocking autoclave. The catalyst was removed by filtration and the filtrate analyzed by glc to show 3.7 g of N-phenyl-N-(3-pyridylmethyl)amine.
Aufarbeitung
- customThe catalyst was removed by filtration
Quellen und Nachweise
- ORD-Eintrag
- ord-8fbdcf1f45c045359af39c90fb58b2ca
- Quelldatensatz
- uspto-grants-1993_10
- Patentnummer
- US05252741
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