2,6-Dichlorobenzyl chloride → 2-(2,6-dichlorophenylmethylthio)pyridine N-oxide

HRID 1657332

Reaktionsgleichung

Reaktionsgleichung von HRID 1657332
[SH:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][N+:3]=1[O-:8].[Na].[Cl:10][C:11]1[CH:18]=[CH:17][CH:16]=[C:15]([Cl:19])[C:12]=1[CH2:13]Cl>C(O)C>[Cl:10][C:11]1[CH:18]=[CH:17][CH:16]=[C:15]([Cl:19])[C:12]=1[CH2:13][S:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][N+:3]=1[O-:8]

Komponenten

5

Edukt 3

HCID 748322,6-Dichlorobenzyl chlorideHCID 5360545SodiumHCID 178526253HCID 178526253, Verbindung

Produkt 1

HCID 124315032-(2,6-dichlorophenylmethylthio)pyridine N-oxideAusbeute 92 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

A mixture of 37 gms (0.1 mole) 2-mercaptopyridine N-oxide, sodium salt (40% aqueous solution) and 19.5 gms (0.1 mole) 2,6-dichlorobenzylchloride in 200 ml of ethanol is warmed to 65° - 70° for 30 minutes, cooled and filtered. The filter cake is washed thoroughly water and finally with 40 ml of acetone. The dry cake (25.3 gms) represents a 92% yield of 2-(2,6-dichlorophenylmethylthio)pyridine N-oxide. Melting point 240° - 241°C. Structure confirmed by IR and NMR.

Aufarbeitung

  1. temperatureis warmed to 65° - 70° for 30 minutes
  2. temperaturecooled
  3. filtrationfiltered
  4. washThe filter cake is washed thoroughly water

Quellen und Nachweise

ORD-Eintrag
ord-59a9de37dfbf4415971c2cf5035fdf17
Quelldatensatz
uspto-grants-1976_06
Patentnummer
US03960542

Verknüpfte Notizen

Wird geladen…