2,6-Dichlorobenzyl chloride → 2-(2,6-dichlorophenylmethylthio)pyridine N-oxide

HRID 1657340

Reaktionsgleichung

Reaktionsgleichung von HRID 1657340
[SH:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][N+:3]=1[O-:8].[Na].[Cl:10][C:11]1[CH:18]=[CH:17][CH:16]=[C:15]([Cl:19])[C:12]=1[CH2:13]Cl>C(O)C>[Cl:10][C:11]1[CH:18]=[CH:17][CH:16]=[C:15]([Cl:19])[C:12]=1[CH2:13][S:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][N+:3]=1[O-:8]

Komponenten

5

Edukt 3

HCID 748322,6-Dichlorobenzyl chlorideHCID 5360545SodiumHCID 178526253HCID 178526253, Verbindung

Produkt 1

HCID 124315032-(2,6-dichlorophenylmethylthio)pyridine N-oxide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

A mixture of 37 gms (0.1 mole) of (40% solution) 2-mercaptopyridine N-oxide, sodium salt and 19.5 gms (0.1 mole) 2,6-dichlorobenzylchloride in 200 ml ethanol is warmed to 65° for thirty minutes, cooled and filtered. The filter cake is washed thoroughly with water and finally with 40 ml of acetone. Vacuum drying of the cake yields 25.3 gms (92% theory) of product, 2-(2,6-dichlorophenylmethylthio)pyridine N-oxide. Melting point 240° - 241°C. Structure confirmed by IR.

Aufarbeitung

  1. temperatureis warmed to 65° for thirty minutes
  2. temperaturecooled
  3. filtrationfiltered
  4. washThe filter cake is washed thoroughly with water and finally with 40 ml of acetone
  5. customVacuum drying of the cake

Quellen und Nachweise

ORD-Eintrag
ord-65d4d13f84b744a9a339e7165b4e4218
Quelldatensatz
uspto-grants-1976_06
Patentnummer
US03960542

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