2-Pyrrolidone → 2-Chloro-10-(1-pyrrolin-2-YL)phenoxazine

Beteiligte Stoffe

Reaktionsschritte

Reaction of 2-chlorophenoxazine, 2-pyrrolidinone, and phosphorus oxychloride according to the procedure of Example 1 provides the free base 2-CHLORO-10-(1-PYRROLIN-2-YL)PHENOXAZINE as a distillable oil, b.p. 150°-165°C. at 0.1 mm Hg. Conversion of the free base to the hydrochloride salt affords 2-CHLORO-10-(1-PYRROLIN-2-YL)-PHENOXAZINE HYDROCHLORIDE, m.p. 209.5°-213.5°C. (corr.), in a 40% overall yield.

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