Sulfuric Acid → Diethyl (2-hydroxyethyl)phosphonate

HRID 1657986Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1657986
[CH2:1]([O:3][P:4]([CH2:9][CH2:10][O:11]C(=O)C)(=[O:8])[O:5][CH2:6][CH3:7])[CH3:2].OS(O)(=O)=O>C(O)C>[CH2:6]([O:5][P:4]([CH2:9][CH2:10][OH:11])(=[O:8])[O:3][CH2:1][CH3:2])[CH3:7]

Komponenten

4

Edukt 2

HCID 1118Sulfuric AcidHCID 124696282-(Diethoxyphosphoryl)ethyl acetate

Produkt 1

HCID 312225Diethyl (2-hydroxyethyl)phosphonateAusbeute 80 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel2×

Versuchsvorschrift

100 g of 2-acetoxyethane phosphonic acid diethyl ester are heated to 80°C jointly with 200 ml of ethanol. To this solution are added dropwise within 5 hours 20 ml of ethanol containing 1 wt.% of H2SO4 while simultaneously removing by continuous distillation a mixture of ethylacetate and ethanol. The residue is submitted to distillation under reduced pressure. 64 g of 2-hydroxyethane-phosphonic acid diethyl ester are obtained, corresponding to a yield of 80% of the theoretical.

Aufarbeitung

  1. customwhile simultaneously removing by continuous distillation
  2. additiona mixture of ethylacetate and ethanol
  3. distillationThe residue is submitted to distillation under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-693111acb26648e3a0c340ae159facb7
Quelldatensatz
uspto-grants-1976_06
Patentnummer
US03962378

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